The smart Trick of ceesdekker That Nobody is Discussing

Using one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we look for to unravel the mechanistic aspects of the framework and dynamics of chromosomes. Our analysis interests involve:

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Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I

2007, initially genuine-time detection of strand Trade in homologous recombination by RecA; discovery of a reduced persistence length of ends of microtubules; and fixed the system of biosensing with carbon nanotubes

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft met veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

‘At first we looked at biological systems having a physical view and acted on the basis of the tools we knew. It took a number of years right before we started working more on the massive Organic difficulties. I then began to connect with it nanobiology, a time period that didn't exist at time.

2011, initial in vitro measurements of transportation across a single biomimetic nuclear pore advanced; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination

2003, demonstrated the 1st biosensors designed from a carbon nanotube; fixed the construction and system of DNA fix proteins; and discovery of a new procedure for fabricating strong-point out nanopores for DNA translocation

Dekker started out his investigate on solitary carbon nanotubes in 1993 when he arrange a fresh line of investigate to study electrical transportation via solitary organic molecules among nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was accomplished in a very collaboration Using the group of Nobel laureate Richard Smalley. STM and nanolithography procedures were accustomed to reveal that these nanotubes are quantum wires at the single-molecule degree, with remarkable Actual physical Qualities.

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2013, controlled shaping of Stay bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations inside the handedness of histone tetrasomes